MCQs PHARMACOLOGY: Drugs used in gastrointestinal diseases

001. Tick the main approach of peptic ulcer treatment: a) Neutralization of gastric acid b) Eradication of Helicobacter pylori c) Inhibition of gastric acid secretion d) All the above

002. Gastric acid secretion is under the control of the following agents EXCEPT: a) Histamine b) Acetylcholine c) Serotonin d) Gastrin

003. Indicate the drug belonging to proton pump inhibitors: a) Pirenzepine b) Ranitidine c) Omeprazole d) Trimethaphan

004. All of the following agents intensify the secretion of gastric glands EXCEPT: a) Pepsin b) Gastrin c) Histamine d) Carbonate mineral waters

005. Which of the following drugs is an agent of substitution therapy? a) Gastrin b) Hydrochloric acid c) Hystamine d) Carbonate mineral waters

006. Choose the drug which is a H2-receptor antagonist: a) Omeprazole b) Pirenzepine c) Carbenoxolone d) Ranitidine

007. All of the following drugs are proton pump inhibitors EXCEPT: a) Pantoprozole b) Omeprazole c) Famotidine d) Rabeprazole

008. Indicate the drug belonging to M1-cholinoblockers: a) Cimetidine b) Ranitidine c) Pirenzepin d) Omeprazole

009. Which of the following drugs may cause reversible gynecomastia? a) Omeprazole b) Pirenzepinec) Cimetidine d) Sucralfate

010. Cimetidine has no effect on hepatic drug metabolism. It’s a) True b) False

011. Tick the drug forming a physical barrier to HCL and Pepsin: a) Ranitidine b) Sucralfate c) Omeprazole d) Pirenzepine

012. Which drug is an analog of prostaglandin E1? a) Misoprostole b) De-nol c) Sucralfate d) Omeprazole

013. Select the drug stimulating the protective function of the mucous barrier and the stability of the mucous membrane against damaging factors: a) De-nol b) Sucralfate c) Misoprostol d) Omeprazole

014. Antacids are weak bases that react with gastric hydrochloric acid to form salt and water. It’s a) True b) False

015. Most of drugs are antacids EXCEPT: a) Misoprostol b) Maalox c) Mylanta d) Almagel

016. Indicate the drug that cause metabolic alkalosis: a) Sodium bicarbonate b) Cimetidine c) Pepto-Bismol d) Carbenoxolone

017. Choose the drug that causes constipation: a) Sodium bicarbonate b) Aluminium hydroxide c) Calcium carbonate d) Magnesium oxide

018. All of the following drugs stimulate appetite EXCEPT: a) Vitamins b) Bitters c) Fepranone d) Insulin

019. Ethyl alcohol is an agent decreasing appetite. It’s: a) True b) False

020. Select an anorexigenic agent affecting serotoninergic system: a) Fenfluramine b) Fepranone c) Desopimone d) Masindole

021. All of the following drugs intensify gastrointestinal motility EXCEPT: a) Papaverine b) Metoclopramide c) Domperidone d) Cisapride

022. Metoclopramide is a potent dopamine antagonist.It’s a) True b) False

023. Choose an emetic drug of central action: a) Ipecacuanha derivatives b) Promethazine c) Tropisetron d) Apomorphine hydrochloride

024. Tick the mechanism of Metoclopramide antiemetic action: a) H1 and H2-receptor blocking effect b) M-cholinoreceptor stimulating effect c) D2-dopamine and 5-HT3-serotonin receptor blocking effect d) M-cholinoblocking effect

025. Select the emetic agent having a reflex action: a) Ipecacuanha derivatives b) Apomorphine hydroclorid c) Chlorpromazine d) Metoclopramide

026. All of the following drugs are antiemetics EXCEPT: a) Metoclopramide b) Ondansetron c) Chlorpromazine d) Apomorphine hydrochloride

027. Indicate an antiemetic agent which is related to neuroleptics: a) Metoclopramide b) Nabilone c) Tropisetron d) Prochlorperazine

028. All of these drugs reduce intestinal peristalsis EXCEPT: a) Loperamide b) Cisapride c) Methyl cellulose d) Magnesium aluminium silicate

029. Indicate the laxative drug belonging to osmotic laxatives: a) Docusate sodium b) Bisacodyl c) Phenolphthalein d) Sodium phosphate

030. The mechanism of stimulant purgatives is: a) Increasing the volume of non-absorbable solid residue b) Increasing motility and secretion c) Altering the consistency of the feces d) Increasing the water content

031. Choose the drug irritating the gut and causing increased peristalsis: a) Phenolphthalein b) Methyl cellulose c) Proserine d) Mineral oil

032. All of the following drugs stimulate bile production and bile secretion EXCEPT: a) Chenodiol b) Cholenszyme c) Oxaphenamide d) Cholosas

033. Tick the stimulant of bile production of vegetable origin: a) Oxaphenamide b) Papaverine c) Cholenzyme d) Cholosas

034. Select the drug which inhibits peristalsis: a) Castor oil b) Bisacodyl c) Loperamide d) Sorbitol

035. Choose the drug affecting the biliary system and relaxing Oddy sphincter: a) Cholosas b) Oxaphenamide c) No-spa d) Cholenzyme