ORAL PATHOLOGY: Rhabdomyosarcoma

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Rhabdomyoma: Predilection for the soft tissues of the head and neck Floor of the mouth, soft palate, tongue & buccal mucosa
Mean age: 50 years (children to older adults)
Asymptomatic Well defined submucosal mass Well demarcated but unencapsulated
The neoplastic cells mimic their normal counterpart (adult) Large eosinophilic granular cell with peripheral nuclei

 

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Rhabdomyosarcoma:
When occurs in head and neck is primarily found in children
It is a rapidly growing mass
May cause pain and parasthesia
Common location: Tongue and soft palate
Histopathology:
Embryonal type (children) consists of primitive round cells in which striations are rarely found Immunohistochemistry demonstrates desmin, actin and myogenin
Treatment: Combination of surgery, radiation and chemotherapy
Survival rate incraese from 10% to 70% with this aggressive treatment approach