Fcps pharmacology past paper ? 2008

68) Which drug do not cause gynaecomasia?

a) Digoxin a

b) Griseofulvin

c) Cimetidine

d) Androgen

e) Estrogen

69) Pt developed Morning stiffness,Photosensitivity,rash which test will be positive?

a) RA

b) ANA

b) antimitochondrial

70) Wht is the end product of glucose breakdown ?

a) Galactose

b) Lactose

c) Fructose

d) Pyruvate d

71) In a pre eclamptic pt which drug is used to lower BP before surgery?

a) Hydralazine a

b) Amlodipine


91) A pregnant women is on Phenytoin,wht is the least likely complication in fetus?

a) Bone deformity

b) Mental retardation b

c) Cleft palate

d) Nail Hypoplasia

92) Anticoagulants are indicated in all EXCEPT:

a) Thrombocytopenia a

b) Cerebral infarction

c) Prolong bed rest

d) DVT


95) Which investigation is least likely done in a suspected case of DIC?

a) Clotting time

b) FDP

c) D-Dimer

d) Platelet count

e) PT e

96) Which drug is not used in Dysmenorrhea?

a) Ibuprofen

b) Mefenamic acid

c) Aspirin

d) COX inhibitor

13)germinal epithelium of ovary contain?

a)cuboidal epithelium a

c)columnar

etc

14)columnar epithelium line which structure?

a)thymus

b)choroid plexus

c)uterine tubes c

15)which method is most helpful in identifying chromosomal abnormalities?

a)karyotyping a

b)u\s

etc

question no





9) Mild CCF symptoms, Monotherapy to be prescribed

ACE-I a

Thiazide

Frusimide

Ca Channel blockers

10)Pregnancy Induced Hypertension, Rx?

Methyldopa

11) Side Effects of ACE inhibitors

Hyperkalemia a

HypoKalemia

Hypercalemia

Hypocalcemia

24) Which drug has a n ATROPINE LIKE ACTION

Physostigmine

Scopolamine

25)Old obese Diabetic, newly diagnosed, choice of Rx?

Biguanides a

Biguanides plus sulphonylurea

Insulin

104) A patient on a psychiatric drug, side effects mentioned, which drug is responsible.

Clorpromazine

SSRI

Etc

105) A man, around 35 brought to emergency, sweating, salivation, Heart rate 45, BP 60/40, whats the treatment.

Atropine (correct) (Organo phosphate poisoning.)

Lignocaine

Digoxin

58) H-K-ATPase pump is blocked by

Omeprazole a

Cimetidine

Bismuth

82) Pheocromocytoma, whats the treatment?

Alpha blockers a

Beta blockers

Both Alpha+ Beta

85) Effects of Insulin on body fat deposits/metabolism

37) Which drug binds to COX-2 recepters and not to COX-1

Aspirin

Indomethacin

Piroxicam

Meloxicam

Ibuprofen

39] A 20 year old girl has developed Galactorrhea due to prolactinoma. Bromocriptine is given to treat it the drug causes

A} Inhibition of prolaction from pituitary gland

B} Decreased prolaction from hypothalamus

C} Inhibition of prolaction from breast

D} Stimulation of prolaction of anterior pituitary

E}

40] An unconscious patient presented in ED does not respond to Naloxone. Which of the following drug has been taken by this patient?

A} Morphine

B} Heroine

C} Pethidine

D} Phenobarbital d

E}

45] Insulin

A} Converts glycogen to glucose

B} Stimulates protein synthesis

C} Stimulates lipolysis

If a drug is taken orally. How will u assess the drug?
a. plasma drug conc
b. blood drug conc
c. urine drug conc

2. Regarding Nitroglycerine, all are true except
a. extensive 1st pass effect
b. venodilator
c. dec venous return
d. dec HR
e. t1/2 is 3-5 min

3. Warfarin, effect inc by
a. Cimetidine



5. Enzyme induction occurs in:
a. liver a
b. kidney
c. heart
d. adrenals

6. Digoxin toxicity
a. Inc K* a
b. Inc Mg*
c. dec Ca**
d. dec Na*
e. alkalosis

7. Secondary active transport occurs thru
a. glucose
b. Na* b
c. K*
d. Urea


9. Capillary permeability is inc by
a. hypertension
b. plasma colloid osmotic pressure b
c. intersitial hydrostatic press
d. altered permeability

10. PG in inflammation dec by:
a. aspirin a
b. corticosteroids
c. phosphodiesterase inhibitors

11. Which is true.
a. all parasymp are cholinergic
b. all sympathetic are adrenergic
c. all post-gang parasymp are cholinergic

22. Loop diuretics + thiazides enhance each others effect ( Dec NaCl abs) at:
a. descending loop of Henle
b. ascending loop of Henle
c. proximal convoluted tubule
d. distal convoluted tubule
e. collecting duct

23. Pt with mild CCF. Treatment started. 1 week later pt complains of severe pain at Rt big toe. Cause:
a. thiazide
b. furosemide
c. ACEi c
d. amiodarone

24. Metastatic pleural effusion. Drug to be given:
a. streptomycin
b. clindamycin
c. corticosteroids c
d. bleomycin

25. Monotherapy for mild CCF:
a. digoxin
b. captopril b
c. nifedipine
d. propranolol

26.Pacemaker for complete heart block. Terminals shd be in:
a. SA node
b. AV node
c. Rt atrium
d. purkinje
e. Rt ventricle ..............(correct) e

27. Infant with renal abnormality (renal artery stenosis). Drug responsible:
a. ACEi
b. Ca** channel blocker
c. amiodarone


32. Lidocaine. MOA?
a. dec abnormal tissue conduction and no effect on normal tissue
b. inc PR interval
c. dec atrial contraction
d. dec AV conduction
e. inc QRS
f. inc QT

33. Class IA antiarrythmic drugs
a. Lidocaine
b. quinidine
c. procainide
d. amiodarone

34. Lidocaine as antiarrrythmic:
a. blocks Na* channels
b. Beta blocker
c. K* channel blocker

35.Verapamil ..... as antiarrythmic ?

36.Drug that inc extracellular K* (moves K* out of the cell):
a. Angiotensin
b. H2CO3
c. Carbonic anhydrase
d. pH
e. exercise

37. Sec K* in renal cells
a. metabolic alkalosis
b. carbonic anhydrase

51. Post menopausal women with brease ca. DOC
a. Tamoxifen


58. Cell wall synthesis inhib
a. Penicillin

59. Sulphonamides inhibit
a. tetrahydrofolate in bacteria

60. Dark urine after starting ATT.
a. Rifampin

61. 1 week after starting of ATT, pt c/o pain in big toe. Reason
a. INH
b. Rifampin
c. Ethambutol
d. PZA

62. Needle inserted at paramedian vertebral canal pierces:
a. ant spinal lig
b. post spinal lig
c. supraspinal lig
d. interspinal log
e. ligamentum flavum

63. Pseudomembrane colitis linked to:
a. clindamycin
b. penicillin
c. cephalosporins
d. erythromycin

64. Regarding chemotherapy all are true, except:
a. often multi therapy is not curative
b. req daily dosing of multiple drugs for long time



72. Blood flow regulation
a. cerebrum > cerebellum > sp. cord
b. sp. cord > cerebellum > cerebrum
c. cerebrum > sp. cord > cerebellum



77. Myocardial toxicity to a L/A?
a. Bupivacaine


.


83. PG released in inflammation are inhibited by:
a. aspirin a
b. corticosteroids
c. serotonin


54] A semiconscious patient is brought to the emergency room. He has history of taking some unknown drug. NaHCO3 reverses the action of the drug. Which drug the pt. has likely taken:
A} Phenobarbital a
B} Phenothiazine
C} Morphine
D} Diazepam
E} Alcohol

 

thanks.can some body give answer.