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MCQs PHARMACOLOGY: ANTIBIOTICS

Discussion in 'Exam Preparation' started by aayisha quddus, Dec 9, 2014.

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  1. aayisha quddus

    aayisha quddus Member

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    001. What does the term “antibiotics” mean: a) Non-organic or synthetic substances that selectively kill or inhibit the growth of other microorganisms b) Substances produced by some microorganisms and their synthetic analogues that selectively kill or inhibit the growth of another microorganisms c) Substances produced by some microorganisms and their synthetic analogues that inhibit the growth of organism cells d) Synthetic analogues of natural substances that kill protozoa and helminthes
    002. General principles of anti-infective therapy are: a) Clinical judgment of microbiological factors b) Definitive identification of a bacterial infection and the microorganism’s susceptibility c) Optimal route of administration, dose, dosing frequency and duration of treatment d) All of the above
    003. Minimal duration of antibacterial treatment usually is: a) Not less than 1 day b) Not less than 5 days c) Not less than 10-14 days d) Not less than 3 weeks
    004. Rational anti-microbial combination is used to: a) Provide synergism when microorganisms are not effectively eradicated with a single agent alone b) Provide broad coverage c) Prevent the emergence of resistance d) All of the above
    005. Mechanisms of bacterial resistance to anti-microbial agents are the following, EXCEPT: a) Active transport out of a microorganism or/and hydrolysis of an agent via enzymes produced by a microorganism b) Enlarged uptake of the drug by a microorganism c) Modification of a drug’s target d) Reduced uptake by a microorganism
    006. The statement, that some microorganisms can develop alternative metabolic pathways for rendering reactions inhibited by the drug, is: a) True b) False
    007. All of the following drugs are antibiotics, EXCEPT: a) Streptomycin b) Penicillin c) Co-trimoxazole d) Chloramphenicol
    008. Bactericidal effect is: a) Inhibition of bacterial cell division b) Inhibition of young bacterial cell growth c) Destroying of bacterial cells d) Formation of bacterial L-form
    009. Which of the following groups of antibiotics demonstrates a bactericidal effect? a) Tetracyclines b) Macrolides c) Penicillins d) All of the above
    010. Bacteristatic effect is: a) Inhibition of bacterial cell division b) Inhibition of young bacterial cells growth c) Destroying of bacterial cells d) Formation of bacterial L-form
    011. Which of the following groups of antibiotics demonstrates a bacteristatic effect: a) Carbapenems b) Macrolides c) Aminoglycosides d) Cephalosporins
    012. Which of the following antibiotics contains a beta-lactam ring in their chemical structure : a) Penicillins b) Cephalosporins c) Carbapenems and monobactams d) All groups
    013. Tick the drug belonging to antibiotics-macrolides: a) Neomycin b) Doxycycline c) Erythromycin d) Cefotaxime
    014. Tick the drug belonging to antibiotics-carbapenems: a) Aztreonam b) Amoxacillin c) Imipinem d) Clarithromycin
    015. Tick the drug belonging to antibiotics-monobactams: a) Ampicillin b) Bicillin-5 c) Aztreonam d) Imipinem
    016. Tick the drug belongs to antibiotics-cephalosporins: a) Streptomycin b) Cefaclor c) Phenoxymethilpenicillin d) Erythromycin
    017. Tick the drug belonging to lincozamides: a) Erythromycinb) Lincomycin c) Azithromycin d) Aztreonam 018. Tick the drug belonging to antibiotics-tetracyclines: a) Doxycycline b) Streptomycin c) Clarithromycin d) Amoxacillin
    019. All of antibiotics are aminoglycosides, EXCEPT: a) Gentamycin b) Streptomycin c) Clindamycin d) Neomycin
    020. Tick the drug belonging to nitrobenzene derivative: a) Clindamycin b) Streptomycin c) Azithromycin d) Chloramphenicol
    021. Tick the drug belonging to glycopeptides: a) Vancomycin b) Lincomycin c) Neomycin d) Carbenicillin 022. Antibiotics inhibiting the bacterial cell wall synthesis are: a) Beta-lactam antibiotics b) Tetracyclines c) Aminoglycosides d) Macrolides
    023. Antibiotic inhibiting bacterial RNA synthesis is: a) Erythromycin b) Rifampin c) Chloramphenicol d) Imipinem
    024. Antibiotics altering permeability of cell membranes are: a) Glycopeptides b) Polymyxins c) Tetracyclines d) Cephalosporins
    025. All of the following antibiotics inhibit the protein synthesis in bacterial cells, EXCEPT: a) Macrolides b) Aminoglycosides c) Glycopeptides d) Tetracyclines
    026. Biosynthetic penicillins are effective against: a) Gram-positive and gram-negative cocci, Corynebacterium diphtheria, spirochetes, Clostridium gangrene b) Corynebacterium diphtheria, mycobacteries c) Gram positive cocci, viruses d) Gram negative cocci, Rickettsia, mycotic infections
    027. Which of the following drugs is a gastric acid resistant: a) Penicillin G b) Penicillin V c) Carbenicillin d) Procain penicillin
    028. Which of the following drugs is penicillinase resistant: a) Oxacillin b) Amoxacillin c) Bicillin-5 d) Penicillin G
    029. All of the following drugs demonstrate a prolonged effect, EXCEPT: a) Penicillin G b) Procain penicillin
    c) Bicillin-1 d) Bicillin-5
    030. Mechanism of penicillins’ antibacterial effect is: a) Inhibition of transpeptidation in the bacterial cell wall b) Inhibition of beta-lactamase in the bacterial cell c) Activation of endogenous proteases, that destroy bacterial cell wall d) Activation of endogenous phospholipases, which leads to alteration of cell membrane permeability
    031. Pick out the beta-lactamase inhibitor for co-administration with penicillins: a) Clavulanic acid b) Sulbactam c) Tazobactam d) All of the above
    032. Cephalosporines are drugs of choice for treatment of: a) Gram-positive microorganism infections b) Gram-negative microorganism infections c) Gram-negative and gram-positive microorganism infections, if penicillins have no effect d) Only bacteroide infections
    033. Carbapenems are effective against: a) Gram-positive microorganisms b) Gram-negative microorganisms c) Only bacteroide infections d) Broad-spectum
    034. All of the following antibiotics are macrolides, EXCEPT: a) Erythromycin b) Clarithromycin c) Lincomycin d) Roxythromycin
    035. Tetracyclins have following unwanted effects: a) Irritation of gastrointestinal mucosa, phototoxicity b) Hepatotoxicity, anti-anabolic effect c) Dental hypoplasia, bone deformities d) All of the above
    036. Tick the drug belonging to antibiotics-aminoglycosides: a) Erythromycin b) Gentamycin c) Vancomycin d) Polymyxin
    037. Aminoglycosides are effective against: a) Gram positive microorganisms, anaerobic microorganisms, spirochetes b) Broad-spectum, except Pseudomonas aeruginosa c) Gram negative microorganisms, anaerobic microorganisms d) Broad-spectum, except anaerobic microorganisms and viruses
    038. Aminoglycosides have the following unwanted effects: a) Pancytopenia b) Hepatotoxicity c) Ototoxicity, nephrotoxicity d) Irritation of gastrointestinal mucosa
    039. Choose the characteristics of chloramphenicol: a) Broad-spectum. Demonstrates a bactericidal effect. b) Influences the Gram-positive microorganisms. Demonstrates a bactericidal effect. c) Influences the Gram-negative microorganisms. Demonstrates a bactericidal effect. d) Broad-spectum. Demonstrates a bacteristatic effect.
    040. Chloramphenicol has the following unwanted effects: a) Nephrotoxicity b) Pancytopenia c) Hepatotoxicity d) Ototoxicity
    041. Choose the characteristics of lincozamides: a) Broad-spectum. Demonstrates a bactericidal effect. b) Influence mainly the anaerobic organisms, Gram negative cocci. c) Broad-spectum. Demonstrates a bacteristatic effect.d) Influence mainly the anaerobic organisms, Gram positive cocci.
    042. Lincozamides have the following unwanted effect: a) Nephrotoxicity b) Cancerogenity c) Pseudomembranous colitis d) Irritation of respiratory organs
    043. Choose the characteristics of vancomicin: a) It is a glycopeptide, inhibits cell wall synthesis active only against Gram-negative bacteria b) It is a glycopeptide, that alters permeability of cell membrane and is active against anaerobic bacteria c) It is a beta-lactam antibiotic, inhibits cell wall synthesis active only against Pseudomonas aeruginosa d) It is a glycopeptide, inhibits cell wall synthesis and is active only against Gram-positive bacteria.
    044. Vancomicin has the following unwanted effects: a) Pseudomembranous colitis b) Hepatotoxicity c) “Red neck” syndrome, phlebitis d) All of the above
    045. Which of the following drugs is used for systemic and deep mycotic infections treatment: a) Co-trimoxazol b) Griseofulvin c) Amphotericin B d) Nitrofungin
    046. Which of the following drugs is used for dermatomycosis treatment: a) Nystatin b) Griseofulvin c) Amphotericin B d) Vancomycin
    047. Which of the following drugs is used for candidiasis treatment: a) Griseofulvin b) Nitrofungin c) Myconazol d) Streptomycin
    048. All of the following antifungal drugs are antibiotics, EXCEPT: a) Amphotericin B b) Nystatin c) Myconazol d) Griseofulvin
    049. Mechanism of Amphotericin B action is: a) Inhibition of cell wall synthesis b) Inhibition of fungal protein synthesis c) Inhibition of DNA synthesis d) Alteration of cell membrane permeability
    050. Azoles have an antifungal effect because of: a) Inhibition of cell wall synthesis b) Inhibition of fungal protein synthesis c) Reduction of ergosterol synthesis d) Inhibition of DNA synthesis
    051. Which of the following drugs alters permeability of Candida cell membranes: a) Amphotericin B b) Ketoconazole c) Nystatin d) Terbinafine
    052. Amfotericin B has the following unwanted effects: a) Psychosis b) Renal impairment, anemia c) Hypertension, cardiac arrhythmia d) Bone marrow toxicity
    053. Tick the drug belonging to antibiotics having a polyene structure: a) Nystatin b) Ketoconazole c) Griseofulvin d) All of the above
    054. All of the following drugs demonstrate a fungicidal effect, EXCEPT: a) Terbinafin b) Amfotericin B c) Ketoconazole d) Myconazol
    055. Characteristics of polyenes are following, except: a) Alter the structure and functions of cell membranes b) Broad-spectrum c) Fungicidal effect d) Nephrotoxicity, hepatotoxicity
    056. Characteristics of Amfotericin B are following, EXCEPT: a) Used for systemic mycosis treatment b) Poor absorption from the gastro-intestinal tract c) Does not demonstrate nephrotoxicity d) Influences the permeability of fungus cell membrane
     
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  2. BLESSED

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    Pls do well to upload the answerss.thanks
     
  3. aayisha quddus

    aayisha quddus Member

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    Sure I will upload them soon working on them right now bizi with some other stuff
     
  4. sanjit kumar

    sanjit kumar New Member Leecher

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    pls give me answer of mcq of antibiotic
     
  5. zahra1234

    zahra1234 Member

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  6. zahra1234

    zahra1234 Member

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